A new herpes drug called ASP2151 could be a brilliant new alternative to the popular antiviral drugs acyclovir or Valtrex. The drug uses a different method to attack the herpes virus and may prevent visible symptoms much more effectively than any other currently available therapeutics.
ASP2151 is a long-awaited helicase primase inhibitor (HPI) drug.
The recent quarterly statement for Astellas brings encouraging news, suggesting that ASP2151 is now going into phase III trials.

At the moment it looks like NanoBio’s cream will reduce the average healing time of a cold sore by over a day. This makes it as good as, or slightly better than, anything else currently available for episodic treatment, including pills like Valtrex.
“NB-001 is an investigational nanoemulsion consisting of high-energy, nanometer-size droplets containing cetylpyridinium chloride, polysorbate, and oil…., the nanoemulsion droplets surround the virus and fuse with the viral envelope, causing membrane disruption and viral destruction.”
Interestingly, if you used it early enough, the study found it might reduce healing …

Harvard Medical School researchers have succeeded in developing a topical treatment that, in mice, wipes out herpes virus, one of the most intractable sexually transmitted human diseases.
Judy Lieberman, professor of pediatrics and a senior investigator at the Immune Disease Institute, has overseen the development of the treatment that uses RNA interference, or RNAi, to disable key genes necessary for herpes virus transmission. That cripples the virus in a molecular two-punch knockout, simultaneously disabling its ability to replicate, as well as the host cell’s ability to take up the virus.
Source: Topical …

The forum herpes-coldsores.com has raised $2,038 for herpes research at the University of Florida. The amount was raised entirely through small donations, averaging around $20 each. Herpes sufferers on the site are determined to band together and push through development towards a more effective treatment for their condition.
Between 50-90% of most populations carry the herpes virus, including the populations of the USA, Canada, and the UK. In places such as Italy the figure is as high as 93% for herpes type-1. Despite the virus being common, it only causes …

Vivagel is a new kind of gel that prevents the initial invasion by an infectious virus. Recent trials on animals have shown it is between 85 and 100 per cent effective at blocking HIV and Herpes (HSV). It’s been shown to be effective against HPV and other conditions. It also has contraceptive properties, at it reduced conception rates by 95% in preclinical studies.
VivaGel had good results in human clinical trials: it appears to be non-toxic, non-irritating, and successful at preventing these STDs. Studies also show that viruses are not evolving …

A microbicide gel has come very close to proving effective at reducing the transmission of HIV. This is the first successful trial of such a gel. The Pro 2000 gel was also found to be active against HSV-2 in vitro and in animal models.
The trial results fell just a few percent short of statistical significance, but scientists think the evidence is compelling:
“subgroup analyses give the researchers some confidence that result is not a statistical fluke — among women who reported they used the gel less then 85% of the time, …

Scientists at Vironova have created an entirely new kind of anti-herpes treatment. The treatment uses called a chemical compound called a maturation inhibitor.
The “maturation inhibitor” antiviral Vironova are developing is potentially effective against all of the herpesviridae — even the six other types we don’t typically think about. This is a very broad target for an antiviral. Vironova says that VN-180 has been presented to major pharmaceutical companies and discussions will proceed during the development of the project.
The scientists are using a unique combination of electron microscopes and …

Bill Halford is an expert in herpes viruses and actually has a potential vaccine strain sitting in the freezer in his laboratory. The basic theory behind Halford’s vaccine is that by deleting a critical gene, he can take the kick out of herpes and then inject you with the weakened version.
Although Halford’s vaccine uses a live herpes virus, and is designed to “infect” you, it would only infect you with a strain of the herpes virus that cannot actually cause any visible disease. You would be continually inoculated against the …