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Topical treatment wipes out herpes with RNAi

27 March 2009 No Comment

Harvard Medical School researchers have succeeded in developing a topical treatment that, in mice, wipes out herpes virus, one of the most intractable sexually transmitted human diseases.

Judy Lieberman, professor of pediatrics and a senior investigator at the Immune Disease Institute, has overseen the development of the treatment that uses RNA interference, or RNAi, to disable key genes necessary for herpes virus transmission. That cripples the virus in a molecular two-punch knockout, simultaneously disabling its ability to replicate, as well as the host cell’s ability to take up the virus.

Source: Topical treatment wipes out herpes with RNAi

There is also an interesting Q&A with the lead researcher on this project, here.

Other news sources for this story:
http://insciences.org/article.php?article_id=3539

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